ZellNet Consulting was founded in 1998 by Sylvia Janetzki, who received her Medical Degree from the Humboldt University in Berlin, Germany. Dr. Janetzki has previously worked at Memorial Sloan-Kettering Cancer Center (MSKCC), Fordham University, and Mount Sinai Hospital in New York, and the Hospital Charité in Berlin, Germany. She has been involved in immune monitoring since the early 1990s, led the laboratory of autologous heat-shock protein gp96 immunization at Charité, and established Elispot as a main monitoring tool for patient trials at MSKCC, where she also set-up the first automated Elispot reader system (Zeiss) in the United States for routine use.

From 2005 to 2015 Dr. Janetzki also coordinated the activities of the Assay Working Group of the Cancer Immunotherapy Consortium (CIC/CRI) for which she established the largest proficiency panel and harmonization program currently available for assays like Elispot, ICS, and HLA-peptide multimer staining. As a results, harmonization guidelines have been established and published for Elispot performance, Elispot plate evaluation, HLA peptide multimer staining and the analysis of fcs files (Gating). A list of relevant publications can be found here.

Dr. Janetzki also belongs to the MIATA (“Minimal Information About T-cell Assays”) core team and has spearheaded the efforts to establish transparency in reporting immune monitoring results in publications. MIATA guidelines have been published.

Under the leadership of Dr. Janetzki, ZellNet comprises a team of dedicated scientists with expert understanding of immune assays as Elispot and ICS and their technical intricacies, detailed knowledge about materials, reagents and equipment for the assay conduct offered by a variety of companies, and unmatched expertise in the evaluation of Elispot/Fluorospot plates and FCS files. Every member is trained by strict standards and driven by highest business ethics. Our guiding principle is to provide our customers with an unsurpassed service and to exceed their expectations.

In an effort to enhance the range of services offered, ZellNet is also providing sample logistics support, as well as statistical analysis for Elispot and Flow Cytometry results.

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